What Is Kratom?
A plain-language explanation of kratom leaf, mitragynine, 7-hydroxymitragynine, and why product concentration matters.
Updated
3 sourcesDirect answer
Kratom refers to the plant Mitragyna speciosa and products made from its leaves. A concentrated product advertised for 7-OH should not be treated as interchangeable with botanical kratom. FDA 7-OH scientific assessment
Why this distinction matters on a 7-OH site
"The Truth About 7-OH" focuses on concentrated 7-hydroxymitragynine while retaining kratom context. FDA's July 2025 announcement specifically distinguished its concentrated 7-OH focus from natural leaf. FDA July 2025 scheduling recommendation
That distinction is not an endorsement of leaf safety. It means a useful risk discussion should identify the actual product rather than treating every kratom-related substance as the same exposure.
Leaf, extract, and enhanced product
Natural leaf contains a mixture of alkaloids, usually dominated by mitragynine. FDA describes 7-OH as a minor constituent and reports it below 2% of total alkaloid content. That denominator is not the weight of the whole leaf. FDA 7-OH scientific assessment
An extract is not automatically a 7-OH isolate, and the word "extract" alone does not explain its composition. Ask for the named ingredients and the amounts per serving; do not infer a leaf-like profile from a botanical label.
Related compounds are not interchangeable
Mitragynine and 7-OH have different receptor activity in laboratory experiments. Their relationship to the same plant does not make equal weights equivalent. Kruegel et al. 2016 receptor study
Avoid converting a leaf amount into a concentrated-product amount. This site does not provide dosing or substitution instructions.
Claimed benefits are not approved treatments
A person's report of relief deserves to be heard without turning it into proof of effectiveness. FDA states that no 7-OH drugs are approved. A medical claim on a package does not establish an approved indication. FDA July 2025 scheduling recommendation
Continue with What Is 7-OH?, Science and Evidence, or Reported Benefits and Consequences.