Regulatory Tracker
Dated 7-OH regulatory context: October 14, 2026 notice of intent, proposed thresholds, existing MGPI controls, and the earliest possible order.
Updated
3 sources
Direct answer
As of October 14, 2026, DEA has published a notice of intent for threshold-based temporary Schedule I control of 7-OH and mitragynine pseudoindoxyl (MGPI). It is not an effective 7-OH scheduling order; the notice says an order may be published on or after November 13, 2026. DEA October 14, 2026 notice of intent
The dated record
- July 29, 2025: FDA announced a scheduling recommendation targeting concentrated 7-OH, distinguishing it from natural leaf. FDA July 2025 scheduling recommendation
- August 26, 2026: DEA temporarily scheduled MGPI without a threshold, according to the October notice's background. DEA October 14, 2026 notice of intent
- October 2026: FDA updated its public-health page to describe revised HHS recommendations and new notices. FDA October 2026 7-OH update
- October 14, 2026: DEA published the revised 7-OH/MGPI notice of intent. DEA October 14, 2026 notice of intent
- November 13, 2026: earliest publication date identified for the contemplated order, not a guaranteed effective date. DEA October 14, 2026 notice of intent
What threshold is proposed?
The notice covers either 7-OH or MGPI alone, or their combined amount when both are present. It proposes control when the amount exceeds 1 mg per gram of solid product or 1 mg per milliliter of liquid, OR when the mitragynine-to-covered-substance mass ratio is below 100:1. DEA October 14, 2026 notice of intent
These are proposed regulatory criteria, not safe-dose instructions. FDA describes the approach as intended to distinguish intentionally concentrated formulations from botanical profiles. FDA October 2026 7-OH update
Do existing controls disappear during the notice period?
No. FDA says the existing August controls on MGPI, MGM-15, and MGM-16 remain in effect during the new notice period and until a new temporary order is issued. This does not turn the pending 7-OH notice into an effective order. FDA October 2026 7-OH update
What this tracker does not determine
This national summary is not a product-specific or state-specific legal opinion. It does not establish that possession, sale, or importation is lawful in your location. State law and other federal requirements must be checked separately.
A recommendation, a notice of intent, and an effective order are different events. Verify the instrument and its date before using the word "ban." Read the linked notice rather than inferring legal status from a product label.
Keep health and legal questions separate
A legal threshold does not establish an approved medical use or a safe exposure. Read Science and Evidence for the health evidence and Get Help for support.